The Occurrence of Intraretinal and Subretinal Fluid in Anterior Ischemic Optic Neuropathy


Tags Neuro
Journal Ophthalmology
Status 審查完成
校稿者 蕭靜熹 醫師

Ophthalmology Volume 130, Number 11, November 2023


這篇文章討論了非動脈性前部缺血性視神經病變(nonarteritic anterior ischemic optic neuropathy NAAION)患者眼內intraretinal和眼下subretinal的液體形成。研究報告指出,NAAION是影響50歲以上人群最常見的視神經病變,其主要特徵為疼痛性單眼急性視力喪失,視盘呈現的盤緣模糊和周圍雷射光刺激幅度減弱。本研究以32名NAAION患者為對象,進行了視功能和眼底成像的觀察和分析。作者觀察到了視网膜周厚度增加的現象,特別強調了這一發現的頻率。研究目的在於評估患者的NAAION疾病演變情況,並進一步了解其視功能和眼底成像變化。觀察發現,有無眼底液體對患者視功能和疾病結果的影響尚不明確。總體而言,在NAAION發作後的時間內,視力大致保持穩定,有些患者眼內和眼下的液體情況有所改善。因此,本文提出需要進一步展開隨機、遮蔽、前瞻性研究以確定類固醇對NAAION患者的效果。

English Abstract

The study discusses the presence of intraretinal and subretinal fluid in patients with nonarteritic anterior ischemic optic neuropathy (NAAION). The condition, characterized by painless unilateral acute vision loss, may involve the formation of fluid and subsequent visual impairment. The use of corticosteroids to reduce optic disc swelling and improve visual outcome has been proposed. The presence of subretinal fluid was found to be associated with extensive optic disc swelling and thinning of retinal layers. The study also discusses the pathogenesis of fluid in NAAION compared to other disorders and proposes a hypothesis related to venous hypertension induced transudation. The authors found no significant difference in visual outcomes between patients treated with corticosteroids and those who were not. The study suggests the need for a randomized prospective study to definitively evaluate the efficacy of steroids in NAAION associated with subretinal fluid.