Outcomes of Zone 3 Open globe Injuries by Wound Extent

Ophthalmology Volume 130, Number 4, April 2023

 

中文摘要

本研究調查了258例眼球開放性創傷患者，以評估創傷部位（分為前、中、後三區）對視力和解剖結果的影響。研究結果顯示，遠端後部傷口（pZ3）的患者視力在3個月時的分布明顯差於aZ3創傷（P <0.004），而多元線性迴歸模型則顯示pZ3位置與較差的視力有關（b = 0.29，95％信賴區間為0.09-0.50，P <0.006），且影響視力的效果持久且具有臨床相關性。此外，年齡、玻璃體出血、葡萄膜脫垂和afferent pupillary defect也與視力有關。本研究結果顯示，後部創傷的視力和解剖結果都較差，並且可能需要進一步的手術治療。

 

English Abstract

This article discusses the outcomes of open globe injuries (OGI) with far posterior Z3 (pZ3) wounds, which are thought to have worse visual and anatomic outcomes. The study found that pZ3 injuries were independently associated with worse visual acuity, in addition to other factors such as age, vitreous hemorrhage, and afferent pupillary defect. These findings improve the prognostic precision for severe OGI cases and will guide future research efforts to optimize surgical decision-making. The study also identified that posterior OGIs were more likely to have or develop retinal detachment and proliferative vitreoretinopathy, as well as significant anatomic disruption, although this effect was not independent on multivariate analysis. The results provide valuable information for patient counseling and may direct surgical decision-making on a case-by-case basis.