Nonlinear Relationship of Retinal Thickness and Visual Acuity in Central Retinal and Hemiretinal Vein Occlusion

中文摘要

本研究旨在探索受中心性視網膜靜脈阻塞（CRVO）或半領域視網膜靜脈阻塞（hemiretinal vascular occlusion, HRVO）引起的黃斑水腫治療期間，由afibercept或bevacizumab治療的眼睛中，中央子場厚度（central subfield thickness, CST）與同時的視力字母分數（visual acuity letter score, VALS）之間是否存在線性關聯?研究結果顯示，CRVO或HRVO眼睛接受抗血管內皮生長因數（VEGF）治療後的CST和VALS之間的關係不是簡單的線性關係。總結來說，在本研究中，CST接近217到256 mm的參與者顯示了最佳的VALS，並且視網膜越薄並不總是與更好的VALS相關。

English Abstract

The content describes a study conducted to investigate the relationship between central subfield thickness (CST) on optical coherence tomography (OCT) and visual acuity letter score (VALS) in eyes treated for macular edema associated with retinal vein occlusion. The study found a nonlinear association between CST and VALS, with turning points observed at different visits. There was a strongly positive correlation to the left of each turning point and a strongly negative correlation to the right. It is noted that a thinner retina is not always better for visual acuity. Overall, there is a nonlinear and modest to strong relationship between central retinal thickness and visual acuity in patients with macular edema.