Comparing the Accuracy of Peripapillary OCT Scans and Visual Fields to Detect Glaucoma Worsening

Ophthalmology Volume 130, Number 6, June 2023

中文摘要

本研究旨在比較視神經盤周圍(peripapillary) OCT掃描和視野檢查（VF）在檢測青光眼惡化方面的準確性。該研究分析使用OCT測量視網膜神經纖維層（RNFL）厚度和使用VF測量平均偏差（mean deviation, MD）的同眼變化速率。在2年期間內診斷惡化時，OCT和VF的準確性均不到50%。OCT的準確性高於VF，在中度惡化時提高5-10個百分點，在快速惡化時提高10-15個百分點。將OCT和VF結合使用可以顯著提高準確性超過17個百分點。該研究建議需要更頻繁的OCT掃描和VF檢查以提高青光眼惡化的診斷準確性，並且依賴OCT和VF的結果可以增加整體準確性。

English Abstract

This study aimed to compare the accuracy of peripapillary OCT scans and visual fields (VF) in detecting glaucoma worsening. The study analyzed the within-eye rates of change in retinal nerve fiber layer (RNFL) thickness using OCT and mean deviation (MD) using VF. The accuracy of both OCT and VF was found to be less than 50% when diagnosing worsening over a 2-year period. OCT showed higher accuracy than VF, with an increase of 5-10 percentage points for moderate worsening (75 percentile) and 10-15 percentage points for rapid worsening (95% percentile). Combining both OCT and VF significantly increased accuracy by more than 17 percentage points. The study suggests that more frequent OCT scans and VF tests are needed to improve the accuracy of diagnosing glaucoma worsening, and relying on both OCT and VF increases overall accuracy.