Comparison of Optical Coherence Tomography Structural Parameters for Diagnosis of Glaucoma in High Myopia

JAMA Ophthalmology Published online May 18, 2023

中文摘要

這項cross sectional 研究旨在確定在高度近視個體中檢測青光眼最有效的光學相干斷層掃描（OCT）參數。該研究從韓國一家單一醫院招募了高度近視的參與者，包括有和無青光眼的患者。測量了每位參與者的黃斑神經節細胞-內膜層（ganglion cell-inner plexiform layer , GCIPL）厚度、視網膜周圍神經纖維層（retinal nerve fiber layer, RNFL）厚度和視神經盤（optic nerve head, ONH）參數。結果顯示，下側額GCIPL厚度在高度近視患者中區分青光眼眼睛具有最高的診斷效用。該研究建議將temporal raphe sign與單一OCT參數相結合，可以進一步提高在高度近視青光眼診斷的準確性。

English Abstract

This cross-sectional study aimed to determine the most effective optical coherence tomography (OCT) parameters for detecting glaucoma in individuals with high myopia. The study recruited participants with high myopia, both with and without glaucoma, from a single hospital in South Korea. Macular ganglion cell-inner plexiform layer (GCIPL) thickness, peripapillary retinal nerve fiber layer (RNFL) thickness, and optic nerve head (ONH) parameters were measured in each participant. The inferotemporal GCIPL thickness was found to have the highest diagnostic utility for discriminating glaucomatous eyes in patients with high myopia. The study suggests that combining the temporal raphe sign with single OCT parameters may further enhance the diagnostic accuracy for glaucoma in high myopia.